Mouse Tat activation kit by CRISPRa

CAT#: GA214560

Tat CRISPRa kit - CRISPR gene activation of mouse tyrosine aminotransferase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Tat
• Locus ID: 234724
• Kit Components:

  GA214560G1, Tat gRNA vector 1 in pCas-Guide-CRISPRa

  GA214560G2, Tat gRNA vector 2 in pCas-Guide-CRISPRa

  GA214560G3, Tat gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_146214
• Synonyms: MGC37772; MGC37789; MGC37790; MGC37819; MGC37828; MGC37842
• Summary: This gene encodes a liver-specific mitochondrial enzyme that catalyzes the conversion of L-tyrosine into p-hydroxyphenylpyruvate. Regulated by glucocorticoid and polypeptide hormones, this gene's expression is affected by deletion of a regulatory region near the albino locus on chromosome 7. Mutations in this gene cause tyrosinemia type II in humans. [provided by RefSeq, Mar 2010]