Mouse C1qtnf5 activation kit by CRISPRa

CAT#: GA214613

C1qtnf5 CRISPRa kit - CRISPR gene activation of mouse C1q and tumor necrosis factor related protein 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: C1qtnf5
• Locus ID: 235312
• Kit Components:

  GA214613G1, C1qtnf5 gRNA vector 1 in pCas-Guide-CRISPRa

  GA214613G2, C1qtnf5 gRNA vector 2 in pCas-Guide-CRISPRa

  GA214613G3, C1qtnf5 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001040631, NM_001040632, NM_001190313, NM_001190319, NM_145613
• Synonyms: Ctrp5
• Summary: The protein encoded by this gene is a member of the C1q/tumor necrosis factor superfamily. This family member is a secretory protein that functions in eye development. Mutations in this gene are thought to underlie the pathophysiology of late-onset retinal degeneration (L-ORD) and early-onset long anterior zonules (LAZ). Bicistronic transcripts composed of the coding sequences for this gene (C1qtnf5) and the membrane-type frizzled-related protein gene (Mfrp) have been identified, and the resulting products can interact with each other. Co-transcription of C1qtnf5 and Mfrp has been observed in both human and mouse. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]