Mouse Itga8 activation kit by CRISPRa

CAT#: GA214982

Itga8 CRISPRa kit - CRISPR gene activation of mouse integrin alpha 8

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Itga8
• Locus ID: 241226
• Kit Components:

  GA214982G1, Itga8 gRNA vector 1 in pCas-Guide-CRISPRa

  GA214982G2, Itga8 gRNA vector 2 in pCas-Guide-CRISPRa

  GA214982G3, Itga8 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001001309, NR_138462
• Synonyms: AI447669
• Summary: This gene encodes a member of the integrin family of cell surface proteins that mediate cellular interactions with the extracellular matrix and other cells. The encoded protein undergoes proteolytic processing to generate the disulfide-linked heterodimeric alpha subunit which, in turn associates with a beta subunit to form the functional integrin receptor. Mice lacking the encoded protein mostly die after birth due to kidney defects, but some of animals that survive exhibit defects in the sensory hair cells of the inner ear. [provided by RefSeq, Aug 2016]