Mouse Abat activation kit by CRISPRa

CAT#: GA215960

Abat CRISPRa kit - CRISPR gene activation of mouse 4-aminobutyrate aminotransferase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Abat
• Locus ID: 268860
• Kit Components:

  GA215960G1, Abat gRNA vector 1 in pCas-Guide-CRISPRa

  GA215960G2, Abat gRNA vector 2 in pCas-Guide-CRISPRa

  GA215960G3, Abat gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001170978, NM_172961
• Synonyms: 9630038C02Rik; AI255750; ENSMUSG00000051226; Gabaat; Gabat; Gm9851; I54; Laibat
• Summary: The encoded gene product is responsible for catabolism of gamma-aminobutyric acid (GABA), a mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. Deficiency of this encoded protein includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010]