Mouse Eif5a activation kit by CRISPRa

CAT#: GA216136

Eif5a CRISPRa kit - CRISPR gene activation of mouse eukaryotic translation initiation factor 5A

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Eif5a
• Locus ID: 276770
• Kit Components:

  GA216136G1, Eif5a gRNA vector 1 in pCas-Guide-CRISPRa

  GA216136G2, Eif5a gRNA vector 2 in pCas-Guide-CRISPRa

  GA216136G3, Eif5a gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001166589, NM_001166590, NM_001166591, NM_001166592, NM_001166593, NM_001166594, NM_001166595, NM_001166596, NM_181582
• Synonyms: AA410058; D19Wsu54e; eIF-4D; eIF-5A; eIF-5A-1; eIF-5A1; Eif4d; Eif5a1
• Summary: This gene encodes an elongation initiation factor, which participates in protein synthesis. The encoded protein also plays roles in mRNA metabolism, cell proliferation, and cell cycle control. This protein contains a modified lysine residue called hypusine, which appears to be necessary for its function. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 2, 5, and 19. [provided by RefSeq, Oct 2009]