Mouse Prdx6b activation kit by CRISPRa

CAT#: GA216563

Prdx6b CRISPRa kit - CRISPR gene activation of mouse peroxiredoxin 6B

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Prdx6b
• Locus ID: 320769
• Kit Components:

  GA216563G1, Prdx6b gRNA vector 1 in pCas-Guide-CRISPRa

  GA216563G2, Prdx6b gRNA vector 2 in pCas-Guide-CRISPRa

  GA216563G3, Prdx6b gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_177256, NR_033713
• Synonyms: 1-cysPrx-P1; 4930414C22Rik; Aop2-rs1; Prdx5-rs1; Prdx6-ps1; Prdx6-rs1; Prdx6-rs1-ps
• Summary: This intronless gene is similar to the multi-exon peroxiredoxin 6 gene located on chromosome 1. It is transcribed and the ORF is intact compared to that of the peroxiredoxin 6 gene. This gene could be considered a transcribed pseudogene based on a failure to detect the protein in vivo in PMID:14644414. However, NCBI is representing the protein due to mass spectrometry data in PMID:18614015, which detected at least one peptide that is specific for this protein. [provided by RefSeq, Mar 2011]