Mouse Chd7 activation kit by CRISPRa

CAT#: GA216568

Chd7 CRISPRa kit - CRISPR gene activation of mouse chromodomain helicase DNA binding protein 7

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Chd7
• Locus ID: 320790
• Kit Components:

  GA216568G1, Chd7 gRNA vector 1 in pCas-Guide-CRISPRa

  GA216568G2, Chd7 gRNA vector 2 in pCas-Guide-CRISPRa

  GA216568G3, Chd7 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001081417, NM_001277149, NM_001355382, NM_001033395
• Synonyms: A730019I05Rik; Cycn; Cyn; Dz; Edy; Flo; Lda; Mt; Obt; RP23-464N23.1; Todo; WBE1; Whi
• Summary: This gene encodes a protein containing two chromodomains and an ATP-binding helicase domain that functions as a regulator of transcription. Mutations in this gene result in an array of development defects, including inner ear problems. Mice defective for this gene exhibit many of the clinical features of the CHARGE syndrome caused by mutations in the homologous gene in human. [provided by RefSeq, Sep 2015]