Mouse Amy2b activation kit by CRISPRa

CAT#: GA217795

Amy2b CRISPRa kit - CRISPR gene activation of mouse amylase 2b

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Amy2b
• Locus ID: 545562
• Kit Components:

  GA217795G1, Amy2b gRNA vector 1 in pCas-Guide-CRISPRa

  GA217795G2, Amy2b gRNA vector 2 in pCas-Guide-CRISPRa

  GA217795G3, Amy2b gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001190403, NM_001190404
• Synonyms: Amy-X; Amy2-2; mAmy2-1; OTTMUSG00000022462
• Summary: Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and polysaccharides, and thus catalyze the first step in digestion of dietary starch and glycogen. The mouse genome has a cluster of several amylase genes that are expressed at high levels in either salivary gland or pancreas. This gene encodes an amylase isoenzyme produced by the pancreas. At least one mouse strain has a non-functional allele of this gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2011]