UBE2C Human Gene Knockout Kit (CRISPR)
CAT#: KN200240RB
UBE2C - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control |
Donor DNA | RFP-BSD |
Symbol | UBE2C |
Locus ID | 11065 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001281741, NM_001281742, NM_007019, NM_181799, NM_181800, NM_181801, NM_181802, NM_181803, NR_104036, NR_104037 |
Synonyms | dJ447F3.2; UBCH10 |
Summary | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is required for the destruction of mitotic cyclins and for cell cycle progression, and may be involved in cancer progression. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been defined on chromosomes 4, 14, 15, 18, and 19. [provided by RefSeq, Aug 2013] |
Documents
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN200240 | UBE2C - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN200240BN | UBE2C - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN200240LP | UBE2C - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN400240 | UBE2C - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
|
GA107604 | UBE2C CRISPRa kit - CRISPR gene activation of human ubiquitin conjugating enzyme E2 C |
USD 1,290.00 |
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