PRSS8 Human Gene Knockout Kit (CRISPR)
CAT#: KN200646BN
PRSS8 - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
USD 1,290.00
4 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control |
Donor DNA | mBFP-Neo |
Symbol | PRSS8 |
Locus ID | 5652 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_002773 |
Synonyms | CAP1; PROSTASIN |
Summary | 'This gene encodes a member of the peptidase S1 or chymotrypsin family of serine proteases. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate via a disulfide bond to form the heterodimeric enzyme. This enzyme is highly expressed in prostate epithelia and is one of several proteolytic enzymes found in seminal fluid. This protease exhibits trypsin-like substrate specificity, cleaving protein substrates at the carboxyl terminus of lysine or arginine residues. The encoded protease partially mediates proteolytic activation of the epithelial sodium channel, a regulator of sodium balance, and may also play a role in epithelial barrier formation. [provided by RefSeq, Feb 2016]' |
Documents
Product Manuals |
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Resources
Other Versions
SKU | Description | Size | Price |
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KN200646 | PRSS8 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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KN200646LP | PRSS8 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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KN200646RB | PRSS8 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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KN400646 | PRSS8 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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GA103831 | PRSS8 CRISPRa kit - CRISPR gene activation of human serine protease 8 |
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