PPAR gamma (PPARG) Human Gene Knockout Kit (CRISPR)
CAT#: KN201538
PPARG - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control |
Donor DNA | GFP-puro |
Symbol | PPAR gamma |
Locus ID | 5468 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001330615, NM_005037, NM_015869, NM_138711, NM_138712, NM_001354666, NM_001354667, NM_001354668, NM_001354669, NM_001354670 |
Synonyms | CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARgamma |
Summary | 'This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]' |
Documents
Product Manuals |
FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN201538BN | PPARG - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN201538LP | PPARG - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN201538RB | PPARG - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN401538 | PPARG - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
|
GA103688 | PPARG CRISPRa kit - CRISPR gene activation of human peroxisome proliferator activated receptor gamma |
USD 1,290.00 |
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