KRAS Human Gene Knockout Kit (CRISPR)
CAT#: KN201958LP
KRAS - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control |
Donor DNA | Luciferase-Puro |
Symbol | KRAS |
Locus ID | 3845 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_004985, NM_033360, NM_001369786, NM_001369787 |
Synonyms | C-K-RAS; c-Ki-ras2; CFC2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; KI-RAS; KRAS1; KRAS2; NS; NS3; RALD |
Summary | 'This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008]' |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN201958 | KRAS - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN201958BN | KRAS - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN201958RB | KRAS - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN401958 | KRAS - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
|
GA102608 | KRAS CRISPRa kit - CRISPR gene activation of human KRAS proto-oncogene, GTPase |
USD 1,290.00 |
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