c Maf (MAF) Human Gene Knockout Kit (CRISPR)
CAT#: KN209247
MAF - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
USD 1,290.00
4 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control |
Donor DNA | GFP-puro |
Symbol | c Maf |
Locus ID | 4094 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001031804, NM_005360 |
Synonyms | c-MAF; CCA4; CTRCT21 |
Summary | 'The protein encoded by this gene is a DNA-binding, leucine zipper-containing transcription factor that acts as a homodimer or as a heterodimer. Depending on the binding site and binding partner, the encoded protein can be a transcriptional activator or repressor. This protein plays a role in the regulation of several cellular processes, including embryonic lens fiber cell development, increased T-cell susceptibility to apoptosis, and chondrocyte terminal differentiation. Defects in this gene are a cause of juvenile-onset pulverulent cataract as well as congenital cerulean cataract 4 (CCA4). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]' |
Documents
Product Manuals |
FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN209247BN | MAF - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN209247LP | MAF - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN209247RB | MAF - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN409247 | MAF - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
|
GA102782 | MAF CRISPRa kit - CRISPR gene activation of human MAF bZIP transcription factor |
USD 1,290.00 |
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