CTLA4 Human Gene Knockout Kit (CRISPR)
CAT#: KN210150
CTLA4 - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
USD 1,290.00
4 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control |
Donor DNA | GFP-puro |
Symbol | CTLA4 |
Locus ID | 1493 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001037631, NM_005214 |
Synonyms | ALPS5; CD; CD152; CELIAC3; CTLA-4; GRD4; GSE; IDDM12 |
Summary | 'This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008]' |
Documents
Product Manuals |
FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN210150BN | CTLA4 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN210150LP | CTLA4 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN210150RB | CTLA4 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN410150 | CTLA4 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
|
GA101056 | CTLA4 CRISPRa kit - CRISPR gene activation of human cytotoxic T-lymphocyte associated protein 4 |
USD 1,290.00 |
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