12 Lipoxygenase (ALOX12) Human Gene Knockout Kit (CRISPR)
CAT#: KN210211BN
ALOX12 - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
USD 1,290.00
4 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control |
Donor DNA | mBFP-Neo |
Symbol | 12 Lipoxygenase |
Locus ID | 239 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_000697 |
Synonyms | 12-LOX; 12S-LOX; LOG12 |
Summary | 'This gene encodes a member of the lipoxygenase family of proteins. The encoded enzyme acts on different polyunsaturated fatty acid substrates to generate bioactive lipid mediators including eicosanoids and lipoxins. The encoded enzyme and its reaction products have been shown to regulate platelet function. Elevated expression of this gene has been observed in pancreatic islets derived from human diabetes patients. Allelic variants in this gene may be associated with susceptibility to toxoplasmosis. Multiple pseudogenes of this gene have been identified in the human genome. [provided by RefSeq, Aug 2017]' |
Documents
Product Manuals |
FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN210211 | ALOX12 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN210211LP | ALOX12 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN210211RB | ALOX12 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN410211 | ALOX12 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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GA100166 | ALOX12 CRISPRa kit - CRISPR gene activation of human arachidonate 12-lipoxygenase, 12S type |
USD 1,290.00 |
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