VPS35 Human Gene Knockout Kit (CRISPR)
CAT#: KN210597LP
VPS35 - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
USD 1,290.00
4 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control |
Donor DNA | Luciferase-Puro |
Symbol | VPS35 |
Locus ID | 55737 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_018206 |
Synonyms | MEM3; PARK17 |
Summary | This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. [provided by RefSeq, Jul 2008] |
Documents
Product Manuals |
FAQs |
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Resources
Other Versions
SKU | Description | Size | Price |
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KN210597 | VPS35 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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KN210597BN | VPS35 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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KN210597RB | VPS35 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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KN410597 | VPS35 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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GA110924 | VPS35 CRISPRa kit - CRISPR gene activation of human VPS35 retromer complex component |
USD 1,290.00 |
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