PAK1 Human Gene Knockout Kit (CRISPR)
CAT#: KN213831RB
PAK1 - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
USD 1,290.00
4 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control |
Donor DNA | RFP-BSD |
Symbol | PAK1 |
Locus ID | 5058 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001128620, NM_002576 |
Synonyms | PAKalpha |
Summary | 'This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Mutations in this gene have been associated with macrocephaly, seizures, and speech delay. Overexpression of this gene is also reported in many cancer types, and particularly in breast cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2020]' |
Documents
Product Manuals |
FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN213831 | PAK1 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN213831BN | PAK1 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN213831LP | PAK1 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN413831 | PAK1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
|
GA103378 | PAK1 CRISPRa kit - CRISPR gene activation of human p21 (RAC1) activated kinase 1 |
USD 1,290.00 |
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