Factor H (CFH) Human Gene Knockout Kit (CRISPR)
CAT#: KN220707
CFH - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control |
Donor DNA | GFP-puro |
Symbol | Factor H |
Locus ID | 3075 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_000186, NM_001014975 |
Synonyms | AHUS1; AMBP1; ARMD4; ARMS1; CFHL3; FH; FHL1; HF; HF1; HF2; HUS |
Summary | 'This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Oct 2011]' |
Documents
Product Manuals |
FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN220707BN | CFH - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN220707LP | CFH - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN220707RB | CFH - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN420707 | CFH - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
|
GA102097 | CFH CRISPRa kit - CRISPR gene activation of human complement factor H |
USD 1,290.00 |
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