POLR2C Human Gene Knockout Kit (CRISPR)

CAT#: KN401317

POLR2C - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.

Product Images

• 

Specifications

Product Data

• Format: 2 gRNA vectors, 1 linear donor
• Donor DNA: EF1a-GFP-P2A-Puro
• Symbol: POLR2C
• Locus ID: 5432
• Disclaimer: The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_002694, NM_032940
• Synonyms: DNA directed RNA polymerase II polypeptide C; hRPB33; hsRPB3; polymerase (RNA) II (DNA directed) polypeptide C (33kD); polymerase (RNA) II (DNA directed) polypeptide C, 33kDa; RNA polymerase II subunit 3; RPB3; RPB3, RPB31, hRPB33, hsRPB3; RPB31
• Summary: 'This gene encodes the third largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a cysteine rich region and exists as a heterodimer with another polymerase subunit, POLR2J. These two subunits form a core subassembly unit of the polymerase. A pseudogene has been identified on chromosome 21. [provided by RefSeq, Jul 2008]'