APPBP1 (NAE1) Human Gene Knockout Kit (CRISPR)
CAT#: KN401326
NAE1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | NAE1 |
Locus ID | 8883 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001018159, NM_001018160, NM_001286500, NM_003905 |
Synonyms | A-116A10.1; APPBP1; HPP1; ula-1 |
Summary | The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN201326 | NAE1 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN201326BN | NAE1 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN201326LP | NAE1 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN201326RB | NAE1 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
GA105916 | NAE1 CRISPRa kit - CRISPR gene activation of human NEDD8 activating enzyme E1 subunit 1 |
USD 1,290.00 |
{0} Product Review(s)
Be the first one to submit a review