ZNF420 Human Gene Knockout Kit (CRISPR)
CAT#: KN401401
ZNF420 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
KN401401 is the updated version of KN201401.
USD 1,290.00
2 Weeks*
Size
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Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | ZNF420 |
Locus ID | 147923 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_144689, NM_001329515, NM_001329516, NM_001329517, NM_001329518, NM_001329519, NM_001329520, NM_001329521, NM_001329522, NM_001329524, NR_138039 |
Synonyms | APAK |
Summary | The protein encoded by this gene is a KRAB-type zinc finger protein that negatively-regulates p53-mediated apoptosis. Under stress conditions, the encoded protein is phosphorylated by ATM and dissociates from p53, which activates p53 and initiates apoptosis. [provided by RefSeq, Jul 2016] |
Documents
Product Manuals |
FAQs |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
GA115639 | ZNF420 CRISPRa kit - CRISPR gene activation of human zinc finger protein 420 |
USD 1,290.00 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.