RBM3 Human Gene Knockout Kit (CRISPR)

CAT#: KN401659

RBM3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.

Product Images

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Specifications

Product Data

• Format: 2 gRNA vectors, 1 linear donor
• Donor DNA: EF1a-GFP-P2A-Puro
• Symbol: RBM3
• Locus ID: 5935
• Disclaimer: The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001017430, NM_001017431, NM_006743
• Synonyms: IS1-RNPL; OTTHUMP00000025800; OTTHUMP00000025802; RNA binding motif (RNP1, RRM) protein 3; RNA binding motif protein 3; RNPL; RNPL, IS1-RNPL
• Summary: 'This gene is a member of the glycine-rich RNA-binding protein family and encodes a protein with one RNA recognition motif (RRM) domain. Expression of this gene is induced by cold shock and low oxygen tension. A pseudogene exists on chromosome 1. Multiple alternatively spliced transcript variants that are predicted to encode different isoforms have been characterized although some of these variants fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq, Jul 2008]'