PDE9A Human Gene Knockout Kit (CRISPR)

CAT#: KN402033

PDE9A - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 linear donor
• Donor DNA: EF1a-GFP-P2A-Puro
• Symbol: PDE9A
• Locus ID: 5152
• Disclaimer: The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001001567, NM_001001568, NM_001001569, NM_001001570, NM_001001571, NM_001001572, NM_001001573, NM_001001574, NM_001001575, NM_001001576, NM_001001577, NM_001001578, NM_001001579, NM_001001580, NM_001001581, NM_001001582, NM_001001583, NM_001001584, NM_001001585, NM_001315533, NM_002606
• Synonyms: HSPDE9A2
• Summary: The protein encoded by this gene catalyzes the hydrolysis of cAMP and cGMP to their corresponding monophosphates. The encoded protein plays a role in signal transduction by regulating the intracellular concentration of these cyclic nucleotides. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]