RAIDD (CRADD) Human Gene Knockout Kit (CRISPR)

CAT#: KN402050

CRADD - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.

SDS

KN2.0 knockout kit validation

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KN402050 is the updated version of KN202050.

USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 2 gRNA vectors, 1 linear donor
Donor DNA EF1a-GFP-P2A-Puro
Symbol CRADD
Locus ID 8738
Disclaimer The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001320099, NM_001320100, NM_001320101, NM_001330126, NM_003805, NR_135147
Synonyms MRT34; RAIDD
Summary This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with cognitive disability. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

Other Versions

SKU Description Size Price
GA105802 CRADD CRISPRa kit - CRISPR gene activation of human CASP2 and RIPK1 domain containing adaptor with death domain
    • 1 kit

USD 1,290.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.