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ATIC Human Gene Knockout Kit (CRISPR)
CAT#: KN403490
ATIC - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
KN403490 is the updated version of KN203490.
USD 1,290.00
2 Weeks*
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Specifications
| Product Data | |
| Format | 2 gRNA vectors, 1 linear donor |
| Donor DNA | EF1a-GFP-P2A-Puro |
| Symbol | ATIC |
| Locus ID | 471 |
| Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
| Reference Data | |
| RefSeq | NM_004044 |
| Synonyms | AICAR; AICARFT; HEL-S-70p; IMPCHASE; PURH |
| Summary | 'This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. [provided by RefSeq, Sep 2009]' |
Documents
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| FAQs |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| GA100328 | ATIC CRISPRa kit - CRISPR gene activation of human 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase |
USD 1,290.00 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.