Livin (BIRC7) Human Gene Knockout Kit (CRISPR)
CAT#: KN404906
BIRC7 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
KN404906 is the updated version of KN204906.
USD 1,290.00
2 Weeks*
Size
Other products for "BIRC7"
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | BIRC7 |
Locus ID | 79444 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_022161, NM_139317 |
Synonyms | KIAP; LIVIN; ML-IAP; MLIAP; RNF50 |
Summary | This gene encodes a member of the inhibitor of apoptosis protein (IAP) family, and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Elevated levels of the encoded protein may be associated with cancer progression and play a role in chemotherapy sensitivity. Alternative splicing results in multiple transcript variants [provided by RefSeq, Jul 2013] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
GA112446 | BIRC7 CRISPRa kit - CRISPR gene activation of human baculoviral IAP repeat containing 7 |
USD 1,290.00 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.