EDG2 (LPAR1) Human Gene Knockout Kit (CRISPR)

CAT#: KN406065

LPAR1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.

Product Images

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Specifications

Product Data

• Format: 2 gRNA vectors, 1 linear donor
• Donor DNA: EF1a-GFP-P2A-Puro
• Symbol: EDG2
• Locus ID: 1902
• Disclaimer: The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001401, NM_057159, NM_001351397, NM_001351398, NM_001351399, NM_001351400, NM_001351401, NM_001351402, NM_001351403, NM_001351404, NM_001351405, NM_001351406, NM_001351407, NM_001351408, NM_001351409, NM_001351410, NM_001351411, NM_001351412, NM_001351413, NM_001351414, NM_001351415, NM_001351416, NM_001351417, NM_001351418, NM_001351419, NM_001351420
• Synonyms: edg-2; EDG2; Gpcr26; GPR26; LPA1; Mrec1.3; rec.1.3; vzg-1; VZG1
• Summary: 'The integral membrane protein encoded by this gene is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion. Two transcript variants encoding the same protein have been identified for this gene [provided by RefSeq, Jul 2008]'