Heparin Cofactor II (SERPIND1) Human Gene Knockout Kit (CRISPR)
CAT#: KN406271
SERPIND1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
KN406271 is the updated version of KN206271.
USD 1,290.00
2 Weeks*
Size
Other products for "Heparin Cofactor II"
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | Heparin Cofactor II |
Locus ID | 3053 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_000185 |
Synonyms | D22S673; HC2; HCF2; HCII; HLS2; LS2; THPH10 |
Summary | 'This gene belongs to the serpin gene superfamily. Serpins play roles in many processes including inflammation, blood clotting, and cancer metastasis. Members of this family have highly conserved secondary structures with a reactive center loop that interacts with the protease active site to inhibit protease activity. This gene encodes a plasma serine protease that functions as a thrombin and chymotrypsin inhibitor. The protein is activated by heparin, dermatan sulfate, and glycosaminoglycans. Allelic variations in this gene are associated with heparin cofactor II deficiency. [provided by RefSeq, Jul 2015]' |
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
GA102080 | SERPIND1 CRISPRa kit - CRISPR gene activation of human serpin family D member 1 |
USD 1,290.00 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.