CAMK2D Human Gene Knockout Kit (CRISPR)

CAT#: KN407454

CAMK2D - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.

Product Images

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Specifications

Product Data

• Format: 2 gRNA vectors, 1 linear donor
• Donor DNA: EF1a-GFP-P2A-Puro
• Symbol: CAMK2D
• Locus ID: 817
• Disclaimer: The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001221, NM_001321566, NM_001321567, NM_001321568, NM_001321569, NM_001321570, NM_001321571, NM_001321572, NM_001321573, NM_001321574, NM_001321575, NM_001321576, NM_001321577, NM_001321578, NM_001321579, NM_001321580, NM_001321581, NM_001321582, NM_001321583, NM_001321584, NM_001321585, NM_001321586, NM_001321587, NM_001321588, NM_001321589, NM_001321590, NM_001321591, NM_001321592, NM_172114, NM_172115, NM_172127, NM_172128, NM_172129
• Synonyms: CAMKD
• Summary: 'The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a delta chain. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Distinct isoforms of this chain have different expression patterns.[provided by RefSeq, Nov 2008]'