Calcium independent Phospholipase A2 (PLA2G6) Human Gene Knockout Kit (CRISPR)
CAT#: KN407546
PLA2G6 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | PLA2G6 |
Locus ID | 8398 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001004426, NM_001199562, NM_003560, NM_001349864, NM_001349865, NM_001349866, NM_001349867, NM_001349868, NM_001349869 |
Synonyms | CaI-PLA2; GVI; INAD1; iPLA2; IPLA2-VIA; iPLA2beta; NBIA2; NBIA2A; NBIA2B; PARK14; PLA2; PNPLA9 |
Summary | The protein encoded by this gene is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells. Several transcript variants encoding multiple isoforms have been described, but the full-length nature of only three of them have been determined to date. [provided by RefSeq, Dec 2010] |
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Other Versions
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KN207546 | PLA2G6 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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KN207546BN | PLA2G6 - human gene knockout kit via CRISPR, HDR mediated |
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KN207546LP | PLA2G6 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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KN207546RB | PLA2G6 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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GA105547 | PLA2G6 CRISPRa kit - CRISPR gene activation of human phospholipase A2 group VI |
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