OAS2 Human Gene Knockout Kit (CRISPR)
CAT#: KN408273
OAS2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
KN408273 is the updated version of KN208273.
USD 1,290.00
2 Weeks*
Size
Other products for "OAS2"
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | OAS2 |
Locus ID | 4939 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001032731, NM_002535, NM_016817 |
Synonyms | MGC78578 |
Summary | 'This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]' |
Documents
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FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
GA103299 | OAS2 CRISPRa kit - CRISPR gene activation of human 2'-5'-oligoadenylate synthetase 2 |
USD 1,290.00 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.