Isoleucyl tRNA synthetase (IARS) Human Gene Knockout Kit (CRISPR)
CAT#: KN412911
IARS - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
KN412911 is the updated version of KN212911.
USD 1,290.00
2 Weeks*
Size
Other products for "Isoleucyl tRNA synthetase"
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | Isoleucyl tRNA synthetase |
Locus ID | 3376 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_002161, NM_013417, NR_073446 |
Synonyms | GRIDHH; IARS1; ILERS; ILRS; IRS; PRO0785 |
Summary | 'Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Alternatively spliced transcript variants have been found. [provided by RefSeq, Nov 2012]' |
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FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
GA102296 | IARS CRISPRa kit - CRISPR gene activation of human isoleucyl-tRNA synthetase |
USD 1,290.00 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.