CCNL2 Human Gene Knockout Kit (CRISPR)

CAT#: KN413824

CCNL2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 linear donor
• Donor DNA: EF1a-GFP-P2A-Puro
• Symbol: CCNL2
• Locus ID: 81669
• Disclaimer: The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001039577, NM_001144867, NM_001144868, NM_001320153, NM_001320155, NM_030937, NR_135154, NM_001350497, NM_001350498, NM_001350499, NM_001350500, NR_146722, NR_146723
• Synonyms: ANIA-6B; CCNM; CCNS; HCLA-ISO; HLA-ISO; PCEE; SB138
• Summary: The protein encoded by this gene belongs to the cyclin family. Through its interaction with several proteins, such as RNA polymerase II, splicing factors, and cyclin-dependent kinases, this protein functions as a regulator of the pre-mRNA splicing process, as well as in inducing apoptosis by modulating the expression of apoptotic and antiapoptotic proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]