TRPM3 Human Gene Knockout Kit (CRISPR)

CAT#: KN413931

TRPM3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 linear donor
• Donor DNA: EF1a-GFP-P2A-Puro
• Symbol: TRPM3
• Locus ID: 80036
• Disclaimer: The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001007470, NM_001007471, NM_020952, NM_024971, NM_206944, NM_206945, NM_206946, NM_206947, NM_206948, NM_001366141, NM_001366144, NM_001366146, NM_001366150, NM_001366152, NM_001366153, NM_001366142, NM_001366143, NM_001366145, NM_001366147, NM_001366148, NM_001366149, NM_001366151, NM_001366154
• Synonyms: GON-2; LTRPC3; MLSN2
• Summary: The product of this gene belongs to the family of transient receptor potential (TRP) channels. TRP channels are cation-selective channels important for cellular calcium signaling and homeostasis. The protein encoded by this gene mediates calcium entry, and this entry is potentiated by calcium store depletion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]