GRAF (ARHGAP26) Human Gene Knockout Kit (CRISPR)
CAT#: KN413996
ARHGAP26 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
KN413996 is the updated version of KN213996.
USD 1,290.00
2 Weeks*
Size
Other products for "ARHGAP26"
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | ARHGAP26 |
Locus ID | 23092 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001135608, NM_015071, NM_001349547, NR_146198 |
Synonyms | GRAF; GRAF1; OPHN1L; OPHN1L1 |
Summary | Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2017] |
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
GA108031 | ARHGAP26 CRISPRa kit - CRISPR gene activation of human Rho GTPase activating protein 26 |
USD 1,290.00 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.