MEF2B (BORCS8-MEF2B) Human Gene Knockout Kit (CRISPR)

CAT#: KN414273

MEF2BNB - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.

Product Images

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Specifications

Product Data

• Format: 2 gRNA vectors, 1 linear donor
• Donor DNA: EF1a-GFP-P2A-Puro
• Symbol: MEF2B
• Locus ID: 4207
• Disclaimer: The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001134794, NM_001134795, NM_005919, NR_015420, NR_027307, NR_027308
• Synonyms: FLJ32599; FLJ46391; MADS box transcription enhancer factor 2, polypeptide B (myocyte enhancer factor 2B); MGC189732; MGC189763; myocyte enhancer factor 2B; RSRFR2; RSRFR2, FLJ32599, FLJ46391, MGC189732, MGC189763
• Summary: 'This gene represents numerous read-through transcripts that span GeneID:729991 and 100271849. Many read-through transcripts are predicted to be nonsense-mediated decay (NMD) candidates, and are thought to be non-coding. Some transcripts are predicted to be capable of translation reinitiation at a downstream AUG, resulting in expression of at least one isoform of myocyte enhancer factor 2B (MEF2B) from this read-through locus. At least one additional MEF2B variant and isoform can be expressed from a downstream promoter, and is annotated on GeneID:100271849. [provided by RefSeq, Oct 2010]'