TRPM7 Human Gene Knockout Kit (CRISPR)
CAT#: KN418043
TRPM7 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | TRPM7 |
Locus ID | 54822 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001301212, NM_017672, NR_149152, NR_149153, NR_149154 |
Synonyms | ALSPDC; CHAK; CHAK1; LTrpC-7; LTRPC7; TRP-PLIK |
Summary | This gene belongs to the melastatin subfamily of transient receptor potential family of ion channels. The protein encoded by this gene is both an ion channel and a serine/threonine protein kinase. The kinase activity is essential for the ion channel function, which serves to increase intracellular calcium levels and to help regulate magnesium ion homeostasis. The encoded protein is involved in cytoskeletal organization, cell adhesion, cell migration and organogenesis. Defects in this gene are a cause of amyotrophic lateral sclerosis-parkinsonism/dementia complex of Guam. The gene may also be associated with defects of cardiac function. [provided by RefSeq, Aug 2017] |
Documents
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN218043 | TRPM7 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN218043BN | TRPM7 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN218043LP | TRPM7 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN218043RB | TRPM7 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
GA110287 | TRPM7 CRISPRa kit - CRISPR gene activation of human transient receptor potential cation channel subfamily M member 7 |
USD 1,290.00 |
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