TRMT1 (TRMU) Human Gene Knockout Kit (CRISPR)
CAT#: KN419032
TRMU - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
KN419032 is the updated version of KN219032.
USD 1,290.00
2 Weeks*
Size
Other products for "TRMU"
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | TRMU |
Locus ID | 55687 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001008568, NM_001008569, NM_001008570, NM_001008571, NM_001282782, NM_001282783, NM_001282784, NM_001282785, NM_018006, NR_104240, NR_104241 |
Synonyms | MGC99627; MTO2; MTU1; TRMT; TRMT1 |
Summary | This nuclear gene encodes a mitochondrial tRNA-modifying enzyme. The encoded protein catalyzes the 2-thiolation of uridine on the wobble positions of tRNA(Lys), tRNA(Glu), and tRNA(Gln), resulting in the formation of 5-taurinomethyl-2-thiouridine moieties. Mutations in this gene may cause transient infantile liver failure. Polymorphisms in this gene may also influence the severity of deafness caused by mitochondrial 12S ribosomal RNA mutations. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
GA110883 | TRMU CRISPRa kit - CRISPR gene activation of human tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
USD 1,290.00 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.