PPIL5 (LRR1) Human Gene Knockout Kit (CRISPR)
CAT#: KN419090
LRR1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
KN419090 is the updated version of KN219090.
USD 1,290.00
2 Weeks*
Size
Other products for "LRR1"
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | LRR1 |
Locus ID | 122769 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_152329, NM_203466, NM_203467, NR_037792, NR_037793 |
Synonyms | 4-1BBLRR; LRR-1; PPIL5 |
Summary | The protein encoded by this gene contains a leucine-rich repeat (LRR). It specifically interacts with TNFRSF9/4-1BB, a member of the tumor necrosis factor receptor (TNFR) superfamily. Overexpression of this gene suppresses the activation of NF-kappa B induced by TNFRSF9 or TNF receptor-associated factor 2 (TRAF2), which suggests that this protein is a negative regulator of TNFRSF9-mediated signaling cascades. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2011] |
Documents
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
GA114786 | LRR1 CRISPRa kit - CRISPR gene activation of human leucine rich repeat protein 1 |
USD 1,290.00 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.