CHIT1 Human Gene Knockout Kit (CRISPR)
CAT#: KN419169
CHIT1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
KN419169 is the updated version of KN219169.
USD 1,290.00
2 Weeks*
Size
Other products for "CHIT1"
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | CHIT1 |
Locus ID | 1118 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001256125, NM_001270509, NM_003465, NR_045784, NR_045785 |
Synonyms | CHI3; CHIT; CHITD |
Summary | 'Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jan 2012]' |
Documents
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
GA100798 | CHIT1 CRISPRa kit - CRISPR gene activation of human chitinase 1 |
USD 1,290.00 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.