Acinus (ACIN1) Human Gene Knockout Kit (CRISPR)
CAT#: KN420699
ACIN1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
KN420699 is the updated version of KN220699.
USD 1,290.00
2 Weeks*
Size
Other products for "ACIN1"
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | ACIN1 |
Locus ID | 22985 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001164814, NM_001164815, NM_001164816, NM_001164817, NM_014977 |
Synonyms | ACINUS; ACN; fSAP152 |
Summary | Apoptosis is defined by several morphologic nuclear changes, including chromatin condensation and nuclear fragmentation. This gene encodes a nuclear protein that induces apoptotic chromatin condensation after activation by caspase-3, without inducing DNA fragmentation. This protein has also been shown to be a component of a splicing-dependent multiprotein exon junction complex (EJC) that is deposited at splice junctions on mRNAs, as a consequence of pre-mRNA splicing. It may thus be involved in mRNA metabolism associated with splicing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
GA107948 | ACIN1 CRISPRa kit - CRISPR gene activation of human apoptotic chromatin condensation inducer 1 |
USD 1,290.00 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.