MTHFD1L Human Gene Knockout Kit (CRISPR)

CAT#: KN423034

MTHFD1L - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.



KN2.0 knockout kit validation

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KN423034 is the updated version of KN223034.

USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 2 gRNA vectors, 1 linear donor
Donor DNA EF1a-GFP-P2A-Puro
Symbol MTHFD1L
Locus ID 25902
Disclaimer The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001242767, NM_001242768, NM_001242769, NM_015440, NM_001350486, NM_001350487, NM_001350488, NM_001350489, NM_001350490, NM_001350491, NM_001350492, NM_001350493, NR_146719, NR_146720
Synonyms dJ292B18.2; FTHFSDC1; MTC1THFS
Summary The protein encoded by this gene is involved in the synthesis of tetrahydrofolate (THF) in the mitochondrion. THF is important in the de novo synthesis of purines and thymidylate and in the regeneration of methionine from homocysteine. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.