NMDAR2A (GRIN2A) Human Gene Knockout Kit (CRISPR)
CAT#: KN423136
GRIN2A - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
KN423136 is the updated version of KN223136.
USD 1,290.00
2 Weeks*
Size
Other products for "NMDAR2A"
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | NMDAR2A |
Locus ID | 2903 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_000833, NM_001134407, NM_001134408 |
Synonyms | EPND; FESD; GluN2A; LKS; NMDAR2A; NR2A |
Summary | 'This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]' |
Documents
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
GA101959 | GRIN2A CRISPRa kit - CRISPR gene activation of human glutamate ionotropic receptor NMDA type subunit 2A |
USD 1,290.00 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.