PXK Human Gene Knockout Kit (CRISPR)

CAT#: KN423483

PXK - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 linear donor
• Donor DNA: EF1a-GFP-P2A-Puro
• Symbol: PXK
• Locus ID: 54899
• Disclaimer: The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001289095, NM_001289096, NM_001289098, NM_001289099, NM_001289100, NM_001289101, NM_017771, NM_001349488, NM_001349489, NM_001349490, NM_001349491, NM_001349492, NM_001349493, NM_001349494, NM_001349495, NM_001349496, NM_001349497, NM_001349498, NM_001349499, NM_001349500, NM_001349501, NM_001349502, NM_001349503, NM_001349504, NM_001349506, NM_001349507, NM_001349508, NM_001349509, NM_001349510, NM_001349511, NM_001349512, NM_001349513, NM_001349514, NM_001349515, NM_001349516, NM_001349517, NM_001349518, NM_001349519, NM_001349520, NM_001349521, NM_001349522, NM_001349524, NM_001349525, NM_001349526, NM_001349527, NM_001349528, NM_001349529, NM_001349530, NM_001349531, NM_001349532, NM_001349533, NM_001349534, NM_001349535, NM_001349536, NM_001349537, NM_001349538, NM_001349539, NM_001349540, NR_146193, NR_146194
• Synonyms: MONaKA
• Summary: This gene encodes a phox (PX) domain-containing protein which may be involved in synaptic transmission and the ligand-induced internalization and degradation of epidermal growth factors. Variations in this gene may be associated with susceptibility to systemic lupus erythematosus (SLE). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]