MBD4 Human Gene Knockout Kit (CRISPR)
CAT#: KN423909
MBD4 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
KN423909 is the updated version of KN223909.
USD 1,290.00
2 Weeks*
Size
Other products for "MBD4"
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | MBD4 |
Locus ID | 8930 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001276270, NM_001276271, NM_001276272, NM_001276273, NM_003925 |
Synonyms | MED1 |
Summary | The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains an MBD domain at the N-terminus that functions both in binding to methylated DNA and in protein interactions and a C-terminal mismatch-specific glycosylase domain that is involved in DNA repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2013] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
GA105951 | MBD4 CRISPRa kit - CRISPR gene activation of human methyl-CpG binding domain 4, DNA glycosylase |
USD 1,290.00 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.