Lubricin (PRG4) Human Gene Knockout Kit (CRISPR)
CAT#: KN426376
PRG4 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
KN426376 is the updated version of KN226376.
USD 1,290.00
2 Weeks*
Size
Other products for "PRG4"
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | PRG4 |
Locus ID | 10216 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001127708, NM_001127709, NM_001127710, NM_001303232, NM_005807 |
Synonyms | CACP; HAPO; JCAP; MSF; SZP |
Summary | The protein encoded by this gene is a large proteoglycan that is synthesized by chondrocytes located at the surface of articular cartilage and by some synovial lining cells. This protein contains both chondroitin sulfate and keratan sulfate glycosaminoglycans. It functions as a boundary lubricant at the cartilage surface and contributes to the elastic absorption and energy dissipation of synovial fluid. Mutations in this gene result in camptodactyly-arthropathy-coxa vara-pericarditis syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
GA106946 | PRG4 CRISPRa kit - CRISPR gene activation of human proteoglycan 4 |
USD 1,290.00 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.