Adarb1 Mouse Gene Knockout Kit (CRISPR)
CAT#: KN500875
Adarb1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
KN500875 is the updated version of KN300875.
USD 1,290.00
2 Weeks*
Size
Other products for "Adarb1"
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | Adarb1 |
Locus ID | 110532 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001024837, NM_001024838, NM_001024839, NM_001024840, NM_130895, NR_004429, NR_021486 |
Synonyms | 1700057H01Rik; Adar2; AW124433; AW558573; BB220382; D10Bwg0447e; Red1 |
Summary | This gene encodes a double-stranded-RNA-specific adenosine deaminase that is involved in editing pre-mRNAs by site-specific conversion of adenosine (A) to inosine (I). Substrates for this enzyme include ionotropic glutamate receptors (GluR2-6) and serotonin receptor (5HT2C). Studies in rodents have shown that this protein can modify its own pre-mRNA by A->I editing to create a novel acceptor splice site, alternative splicing to which results in down regulation of its protein expression. Additional splicing events result in transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
GA212323 | Adarb1 CRISPRa kit - CRISPR gene activation of mouse adenosine deaminase, RNA-specific, B1 |
USD 1,290.00 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.