Bad Mouse Gene Knockout Kit (CRISPR)

CAT#: KN501954

Bad - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated.

SDS

KN2.0 knockout kit validation

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KN501954 is the updated version of KN301954.

USD 1,290.00

2 Weeks*

Size
    • 1 kit

Product Images

Specifications

Product Data
Format 2 gRNA vectors, 1 linear donor
Donor DNA EF1a-GFP-P2A-Puro
Symbol Bad
Locus ID 12015
Disclaimer The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001285453, NM_007522
Synonyms AI325008; Bbc2
Summary Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways. [UniProtKB/Swiss-Prot Function]

Other Versions

SKU Description Size Price
GA200364 Bad CRISPRa kit - CRISPR gene activation of mouse BCL2-associated agonist of cell death
    • 1 kit

USD 1,290.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.