Eif4h Mouse Gene Knockout Kit (CRISPR)
CAT#: KN505133
Eif4h - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
KN505133 is the updated version of KN305133.
USD 1,290.00
2 Weeks*
Size
Other products for "Eif4h"
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | Eif4h |
Locus ID | 22384 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001312867, NM_033561 |
Synonyms | AU018978; D5Ertd355e; E430026L18Rik; Ef4h; eIF-4H; Wbscr1; Wscr1 |
Summary | This gene encodes eukaryotic translation initiation factor 4H (eIF4H) that plays a critical role in the process of protein synthesis. The encoded protein is an RNA-binding protein that, in concert with other translation initiation factors, helps unwind the 5' cap-proximal region of mRNA to prepare it for ribosomal attachment. Mice lacking the encoded protein displayed growth retardation with a significant reduction of body weight, a smaller brain volume and altered brain morphology. Behaviorally, mice lacking the encoded protein exhibit severe impairments of fear-related associative learning and memory formation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
GA204622 | Eif4h CRISPRa kit - CRISPR gene activation of mouse eukaryotic translation initiation factor 4H |
USD 1,290.00 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.