Fndc5 Mouse Gene Knockout Kit (CRISPR)
CAT#: KN506047
Fndc5 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
KN506047 is the updated version of KN306047.
USD 1,290.00
2 Weeks*
Size
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Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | Fndc5 |
Locus ID | 384061 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_027402 |
Synonyms | 1500001L03Rik; AI836596; C87088; PeP; Pxp |
Summary | This gene encodes a type I transmembrane protein containing fibronectin type III repeat. The encoded transmembrane protein undergoes proteolytic processing to generate a soluble hormone named irisin that is secreted into the bloodstream. The expression of this gene followed by the secretion of irisin from skeletal muscle is induced by exercise. The ectopic expression of the encoded protein in mice causes an elevation of irisin in blood and improves metabolic health. [provided by RefSeq, Jul 2016] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
GA217278 | Fndc5 CRISPRa kit - CRISPR gene activation of mouse fibronectin type III domain containing 5 |
USD 1,290.00 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.